Menaquinone 7 ≥98%Proveedor: Cayman Chemical
Menaquinone 7 (MK-7) is a vitamin K2 analog that has been found in a variety of fermented foods. It increases osteocalcin, osteoprotegerin, and RANKL mRNA expression in osteoblastic MC3T3E cells. MK-7 (1 µM) increases alkaline phosphatase activity and calcium content in femoral-metaphyseal tissues isolated from normal and skeletal-unloaded rats. In vivo, MK-7 (100 µg/g diet) inhibits aortic and myocardial calcification and decreases aortic alkaline phosphatase tissue concentrations in a rat model of extraosseous calcification. It also increases trabecular number, bone mineral density, and bone mineral content in a rat model of ovariectomy-induced bone loss.
- Formulation: A crystalline solid
- UV/Vis: λmax 248, 270, 330 nm
- Stability: ≥ 2 years
Precaución: This product is not for human or veterinary use.
MW: 649,0 g/mol
Temperatura de almacenaje: Congelador
Núm. CAS: 2124-57-4