Paclitaxel ≥98%

Proveedor: Enzo Life Sciences

ALEXBML-T104-0250EA 1133 EUR
ALEXBML-T104-0250 ALEXBML-T104-0005 ALEXBML-T104-0025
Paclitaxel ≥98%
Paclitaxel

Ultra-pure; stabilizes microtubules


Antitumor agent. Stabilizes microtubules and lowers the critical concentration for tubulin polymerization. Reversibly binds to polymerized tubulin. Inhibits protein isoprenylation and induces apoptosis in PC-3 human prostate cancer cells. The checkpoint of mitotic spindle assembly, aberrant activation of cyclin-dependent kinases (CKDs) and the c-Jun N-terminal kinase/stress activated protein kinase (JNK/SAPK) are involved in Paclitaxel-induced apoptosis.


Isolated from the bark of the Pacific Yew tree (Taxus brevifolia)

Formula: C₄₇H₅₁NO₁₄
MW: 853,91 g/mol
Número MDL: MFCD00869953
Núm. CAS: 33069-62-4
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