Anti-MCAM Mouse Monoclonal Antibody (CF405S) [clone: MCAM/1101]

Proveedor: Biotium

BNC041101-100EA 192 EUR
BNC041101-100 BNC041101-500
Anti-MCAM Mouse Monoclonal Antibody (CF405S) [clone: MCAM/1101]
Anticuerpos
The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2 -independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.

Type: Primary
Antigen: MCAM
Clonality: Monoclonal
Clone: MCAM/1101
Conjugation: CF405S
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human
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