Anti-beta synuclein Rabbit Polyclonal Antibody

Proveedor: Biosensis
BSENR-1683-500EA 345 EUR
BSENR-1683-500
Anti-beta synuclein Rabbit Polyclonal Antibody
Anticuerpos
Beta-synuclein is a soluble cytoplasmic protein associated with synaptic vesicles and a member of the synuclein family. Mutations in alpha-synuclein cause early onset Parkinson's disease. Expression of beta synuclein may modulate alpha-synuclein aggregation found in Parkinson's disease.

Confirmed by WB using soluble mouse and human brain extracts, reactivity for major product diminished by peptide absorption. Does not detect alpha-synuclein as tested with recombinant protein and does not react with Lewy bodies in human Dementia with Lewy Bodies or Parkinson's disease brain tissue sections.
Application Information:
WB and IHC. A dilution of 1:500 to 1:1,000 is recommended for Western blot. Beta-synuclein is a soluble protein of 134 amino acids and detected with 17 kDa mobility by western blotting. By IHC the antibody detects synaptic sites in human brain formaldehyde-treated frozen tissue. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.

Type: Primary
Antigen: beta synuclein
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: C-terminal domain
Host: Rabbit
Isotype: IgG
Reactivity:
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