Hormone Sensitive Lipase (HSL) hydrolyzes stored triglycerides to free fatty acids in adipose tissue and heart. In steroidogenic tissues, HSL principally converts cholesteryl esters to free cholesterol for steroid hormone production (ref: SWISSPROT).
This antibody detects HSL at approx 83-84 kDa in various fat cell lysates from mouse and rat. Additional weaker band may appear at approx 40 kDa (unknown).
Application Information:
WB. Suggested dilution at 1:1,000 to 1:5,000. Biosensis recommends that the optimal working dilution should be determined by the end user.
Type: Primary
Antigen: Hormone Sensitive Lipase
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: Multiple peptide epitopes cooresponding to amino acids 617-828, 533-544 rat, and 191-202 of Mouse HSL protein.
Host: Chicken
Isotype: IgY
Reactivity: Mouse