Anti-Neurotrophin-4/5; NT4/NT5 Chicken Polyclonal Antibody

Proveedor: Biosensis
BSENC-1514-500EA 312 EUR
Anti-Neurotrophin-4/5; NT4/NT5 Chicken Polyclonal Antibody
NT4 is a member of the neurotrophin family, in knockout animals NT4 deficient mice appeared little changed from wildtype animals, however NT4 is a powerful neurotrophic factor for periferial neuronal ganglia and is capable if sustaining ganglia neurons in vitro. NT4 is closely related to both NGF and BDNF. FUNCTION: Target-derived survival factor for peripheral sensory sympathetic neurons. SUBCELLULAR LOCATION: Secreted protein. TISSUE SPECIFICITY: Highest levels in prostate, lower levels in thymus, placenta, and skeletal muscle. Expressed in embryonic and adult tissues. SIMILARITY: Belongs to the NGF-beta family.

The antibody reacts with human and mouse NT-4//5 proteins and likely with other species based upon homology. The antibody has not been tested in IHC or western blot
Application Information:
ELISA at suggested dilution of 1:500-1:2,000. Biosensis recommends that the optimal working dilution should be determined by the end user.

Type: Primary
Antigen: Neurotrophin-4/5; NT4/NT5
Clonality: Polyclonal
Conjugation: Unconjugated
Epitope: Human NT4/5 peptides, amino acids 104-118 and 198-210
Host: Chicken
Isotype: IgY
Reactivity: Human, Mouse
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