Anti-Neurofilament Heavy Chicken Polyclonal Antibody

Proveedor: Biosensis
BSENC-1386-50EA 302 EUR
Anti-Neurofilament Heavy Chicken Polyclonal Antibody
Neurofilaments contain three intermediate filament proteins: light (68 kDa), medium (160 kDa) and heavy (200 kDa). Neurofilament heavy (NF200 or NF-H) is phosphorylated and it is thought that this results in the formation of interfilament cross bridges that are important in the maintenance of axonal caliber. This antibody binds primarily to the phosphorylated axonal forms of NF-H.

This antibody reacts with phosphorylated NF-H and is seen as a band of approx 200 kDa in WB. Refer to publication by Shaw et al (2005) for the use of this antibody in an ELISA to detect NF-H.
Application Information:
Western Blotting (WB), Immunocytochemistry (IC) and ELISA. Suggested dilution for WB is 1:100,000-1,000,000. Suggested dilution for IC is 1:50,000-100,000. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.

Type: Primary
Antigen: Neurofilament Heavy
Clonality: Polyclonal
Conjugation: Unconjugated
Epitope: Multiple points of reactivity likely because of the polyclonal nature of the antibody
Host: Chicken
Isotype: IgY
Reactivity: Human, Rat, Mouse, Cat, Chicken
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