Anti-Presenilin 1 Chicken Polyclonal Antibody

Proveedor: Biosensis
BSENC-1534-500EA 345 EUR
BSENC-1534-500
Anti-Presenilin 1 Chicken Polyclonal Antibody
Anticuerpos
Presenilin-1 (PSEN1) is a multi-pass membrane protein and component of the gamma-secretase complex. PSEN1 is thought to play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. It may also play a role in hematopoiesis. Defects in PSEN1 are a cause of Alzheimer disease type 3 (AD3), a familial early-onset form of Alzheimer disease (Ref:SWISS-Prot).

Antibody recognizes Presenillin-1 in western blot and by ELISA, other applications have not yet been tested.
Application Information:
WB and ELISA. Suggested dilution of 1:1,000 to 1:4,000. To minimise background staining, a higher concentration of detergent (such as Tween-20) is suggested in the dilution and washing steps. Biosensis recommends that the optimal working dilution should be determined by the end user.

Type: Primary
Antigen: Presenilin 1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: Multiple epitopes because of the nature of the immunogen
Host: Chicken
Isotype: IgY
Reactivity: Human, Mouse, Rat
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