Anti-Protein kinase minibrain homolog Mouse Monoclonal Antibody [clone: 7D10]

BSENM-829-100EA 327 EUR
Anti-Protein kinase minibrain homolog Mouse Monoclonal Antibody [clone: 7D10]
Protein kinase minibrain homolog phosphorylates serine, threonine and tyrosine residues in its sequence as well as in exogenous substrates. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. There are 5 named isoforms produced by alternative splicing. It is expressed ubiquitously with highest levels in skeletal muscle, testis, fetal lung and kidney, and in the developing central nervous system. It localises to the nucleus speckle. This protein is overexpressed 1.5-fold in fetal Down syndrome brain and considered a strong candidate for learning defects associated with Down syndrome. It belongs to the protein kinase superfamily, CMGC ser/Thr protein kinase family and MNB/DYRK subfamilly.

Specificity has been confirmed by WB and direct ELISA against the antigen.
Application Information:
Direct and sandwich ELISA and WB are recommended for this antibody. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.

Type: Primary
Antigen: Protein kinase minibrain homolog
Clonality: Monoclonal
Clone: 7D10
Conjugation: Unconjugated
Host: Mouse
Reactivity: Mouse, Rat
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