Anti-ASCL1 Mouse Monoclonal Antibody [clone: 3D3]

Proveedor: Biosensis
BSENM-803-100EA 327 EUR
Anti-ASCL1 Mouse Monoclonal Antibody [clone: 3D3]
This protein plays a role in neuronal commitment and differentiantion in most regions of the CNS and of several neuronal lineages in the PNS. It is also essential for the generation of olfactory and autonomic neurons. The unprocessed precursor is 236 amino acids in length and 25.45KDa. ASCL1 contains one basic helix-loop-helix (bHLH) domain. It activates transcription by binding to the Ebox (5'-CANNTG-3') and efficient DNA binding requires dimerisation with other bHLH proteins. It forms a heterodimer with TCF3.

The specificity of this antibody was confirmed by WB and ELISA against the recombinant protein with the GST tag. GST tag alone was used as a negative control.
Application Information:
This antibody is recommended for WB, ELISA and sandwich ELISA. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.

Type: Primary
Antigen: ASCL1
Clonality: Monoclonal
Clone: 3D3
Conjugation: Unconjugated
Epitope: Human ASCL1 (amino acids 137 to 237)
Host: Mouse
Reactivity: Human
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