Anti-PAFAH alpha Mouse Monoclonal Antibody [clone: 2C12]

BSENM-855-100EA 327 EUR
Anti-PAFAH alpha Mouse Monoclonal Antibody [clone: 2C12]
PAFAH alpha encodes the non-catalytic alpha subunit of the intracellular Ib isoform of platelet-activating factor acteylhydrolase, a heterotrimeric enzyme that specifically catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor. Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist: one composed of multiple subunits, the other, a single subunit. In addition, a single-subunit isoform of this enzyme is found in serum. It is expressed ubiquitously in both the frontal and occipital areas of the brain. Defects in PAFAH alpha cause lissencephaly type 1 (LIS1) and of subcortical band heterotopia (SBH). Defects in PAFAH alpha are also a cause of Miller-Dieker lissencephaly syndrome (MLDS).

Specificity has been confirmed by WB and direct ELISA against the antigen.
Application Information:
This antibody is recommended for WB and sandwich ELISA. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.

Type: Primary
Antigen: PAFAH alpha
Clonality: Monoclonal
Clone: 2C12
Conjugation: Unconjugated
Host: Mouse
Reactivity: Human
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