Ephrin-A5 is a member of the ephrin (EPH) gene family. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. EPH receptors typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. Ephrin-A5 prevents axon bundling in cocultures of cortical neurons with astrocytes, a model of late stage nervous system development and differentiation.
Specificity has been confirmed by WB and direct ELISA against the antigen.
Application Information:
This antibody is recommended for WB, and sandwich ELISA. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
Type: Primary
Antigen: Ephrin-A51
Clonality: Monoclonal
Clone: 1F12
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype:
Reactivity: Mouse