Anti-Ephrin type-B receptor 2 Mouse Monoclonal Antibody [clone: 4D1]

BSENM-834-100EA 327 EUR
BSENM-834-100
Anti-Ephrin type-B receptor 2 Mouse Monoclonal Antibody [clone: 4D1]
Anticuerpos
Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin type-B receptor 2 is a receptor for members of the ephrin-B family and it acts as a tumor suppressor. It is a single-pass type I membrane protein that is expressed in brain, heart, lung, kidney, placenta, pancreas, liver and skeletal muscle. It is preferentially expressedd in fetal brain. Defects in this protein are involved in the development of prostate cancer metastasis to the brain.

Specificity has been confirmed by WB and direct ELISA against the antigen.
Application Information:
This antibody is recommended for WB, and ELISA. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.

Type: Primary
Antigen: Ephrin type-B receptor 2
Clonality: Monoclonal
Clone: 4D1
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype:
Reactivity: Mouse
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