Anti-NF-H Mouse Monoclonal Antibody [clone: 2E8]

Proveedor: Biosensis
BSENM-848-100EA 327 EUR
Anti-NF-H Mouse Monoclonal Antibody [clone: 2E8]
Neurofilaments contain three intermediate filament proteins: L, M and H, which are involved in the maintenance of the neuronal caliber. NF-H has an important function in mature axons. NF-H is phosphorylated and it is thought that this results in the formation of interfilament cross bridges that are important in the maintenance of axonal caliber. Defects in NF-H are a cause of amyotrophic lateral sclerosis (ALS) which is a neurodegenerative disorder affecting upper and lower motor neurons and results in fatal paralysis.

Specificity has been confirmed by WB and direct ELISA against the antigen.
Application Information:
This antibody is recommended for WB and sandwich ELISA. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.

Type: Primary
Antigen: NF-H
Clonality: Monoclonal
Clone: 2E8
Conjugation: Unconjugated
Host: Mouse
Reactivity: Human
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