Anti-Interleukin 6 Mouse Monoclonal Antibody [clone: 3E4]

BSENM-842-100EA 327 EUR
Anti-Interleukin 6 Mouse Monoclonal Antibody [clone: 3E4]
Interleukin 6 (IL-6) is a cytokine with many biological functions. Some of its roles include the final differentiation of B-cells into Ig-secreting cells, induction of meloma and plasmacytoma growth, induction of nerve cell differentiation, and in hepatocytes, induction of acute phase reactants. IL-6 is secreted and is N- and O-glycosylated post translationally. Genetic variations in IL-6 can be correlated with bone mineral density and low bone mineral density is a risk factor for osteoporosis. Defects in IL-6 are associated with juvenile rheumatoid arthritis and at least one polymorphism in IL-6 makes HIV-infected men susceptible to Kaposi sarcoma which is a relatively rare malignant tumour.

Specificity has been confirmed by WB and direct ELISA against the antigen.
Application Information:
This antibody is recommended for WB and ELISA. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.

Type: Primary
Antigen: Interleukin 6
Clonality: Monoclonal
Clone: 3E4
Conjugation: Unconjugated
Host: Mouse
Reactivity: Human
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