Anti-Secretogranin-5 Mouse Monoclonal Antibody [clone: 8G11]

Proveedor: Biosensis
BSENM-865-100EA 327 EUR
Anti-Secretogranin-5 Mouse Monoclonal Antibody [clone: 8G11]
Secretogranin-5 is an acidic protein of 186 amino aids and has an expression that seems to be restricted to neurons and endocrine cells. In the brain, it is most abundant in the supraoptic and paraventricular nuclei of the hypothalamus. It acts in neuroendocrine cells as a specific chaperone for proprotein convertase-2 (PC2) which is an important endoprotease involved in the processing of neuroendocrine precursors. It binds to inactive proPC2 in the ER and facilitates its movement toward the secretory pathway where proPC2 is proteolytically matured and activated. It also plays a role in regulating pituitary hormone secretion.

Specificity has been confirmed by WB and direct ELISA against the antigen.
Application Information:
This antibody is recommended for WB and direct ELISA. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.

Type: Primary
Antigen: Secretogranin-5
Clonality: Monoclonal
Clone: 8G11
Conjugation: Unconjugated
Host: Mouse
Reactivity: Human, Mouse, Rat
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