Anti-Radical fringe homolog Mouse Monoclonal Antibody [clone: 6C7]

BSENM-861-100EA 327 EUR
Anti-Radical fringe homolog Mouse Monoclonal Antibody [clone: 6C7]
The Drosophila melanogaster 'fringe' gene is a secreted signaling protein that is involved in the formation of boundaries between groups of cells during development. It acts by modulating the activation of te Notch signal transduction pathway. A human radical fringe homolog was identified in 1997. There is evidence to show that radical fringe homolog may be involve in limb formation and in neurogenesis in humans. It is a glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. It is a single-pass type II membrane protein which localises to the golgi apparatus membrane. It belongs to the glycosyltransferase 31 family. Its new name is Beta-1,3-N-acetylglucosaminyltransferase radical fringe

Specificity has been confirmed by WB and direct ELISA against the antigen.
Application Information:
This antibody is recommended for WB, immunofluorescence and direct ELISA. The recommended dilution for this antibody is 10 µg/ml for immunofluorescence. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.

Type: Primary
Antigen: Radical fringe homolog
Clonality: Monoclonal
Clone: 6C7
Conjugation: Unconjugated
Host: Mouse
Reactivity: Human
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