Anti-DRP-3 Mouse Monoclonal Antibody [clone: 1B8]

BSENM-826-100EA 327 EUR
Anti-DRP-3 Mouse Monoclonal Antibody [clone: 1B8]
DRP-3 belongs to the hydantoinase/dihydropyrimidase subfamily. It is required for signalling by class 3 semaphorins and remodelling of the cytoskeleton. It also plays a role in axon guidance, neuronal growth cone collapse and cell migration. It exists as a homotetramer, and heterotetramer with CRMP1, DPYSL2, DPYSL4 or DPYSL5. The unprocessed precursor is 570 amino acids long and has an estimated molecular weight of 61.9kDa. It is mainly expressed in heart and skeletal muscle but is also strongly expressed in fetal brain and spinal cord. It localises to the cytoplasm and growth cone. This protein interacts with synaptic vesicle protein 2 and SH3A domain of intersectin.

The specificity of this antibody has been shown by WB and ELISA against the GST tagged recombinant DRP-3 protein.
Application Information:
This antibody is recommended for WB and direct ELISA. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.

Type: Primary
Antigen: DRP-3
Clonality: Monoclonal
Clone: 1B8
Conjugation: Unconjugated
Host: Mouse
Reactivity: Mouse, Rat
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