MSGA belongs to the intercrine alpha (chemokine CXC) familly. In this family, the first two of the four conserved residues are separated by a single amino acid. MSGA has chemotactic activity for neutrophils and may play a role in inflammation. MSA is secreted and subsequently proteolytically processed at the N-terminus by peripheral blood monocytes to form GRO-alpha(4-73), GRO-alpah(5-73) and GRO-alpha(6-73). In vitro, these processed forms show a 30 fold increase in chemotactic activity. The unprocessed precursor has a length of 107 amino acids and a predicted molecular weight of 11.3KDa.
The specificity of this antibody has been confirmed by WB and ELISA against the GST tagged recombinant human MSGA protein.
Application Information:
This antibody is recommended for WB and sandwich ELISA. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
Type: Primary
Antigen: MSGA
Clonality: Monoclonal
Clone: 7A11
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype:
Reactivity: