FUNCTION: Seems to promote the survival of visceral and proprioceptive sensory neurons. SUBCELLULAR LOCATION: Secreted protein. TISSUE SPECIFICITY: Brain and peripheral tissues. SIMILARITY: Belongs to the NGF-beta family.
A cross reactivity of less than 0.1% to mouse NGF, recombinant human BDNF and NT4/5 has been shown by dot blot.
Application Information:
IHC, ELISA, WB, inhibition of biological activity. A dilution of 1:500 to 1:2000 is recommended for IHC, western blot. For inhibition of biological activity: 1:10-50 for in vitro, 5-10 µl/g body weight for in vivo. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
Type: Primary
Antigen: NT3
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: aa: 139-149), Mouse and rat NT3
Host: Rabbit
Isotype: IgG
Reactivity: Rat, Chicken, Human