Anti-Neurokinin-3 Receptor Rabbit Polyclonal Antibody

Proveedor: Biosensis
BSENR-103-100EA 334 EUR
BSENR-103-100
Anti-Neurokinin-3 Receptor Rabbit Polyclonal Antibody
Anticuerpos
FUNCTION: This is a receptor for the tachykinin neuropeptide neuromedin K (neurokinin B). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. SUBCELLULAR LOCATION: Membrane; multi-pass membrane protein. PTM: The anchoring of this receptor to the plasma membrane is probably mediated by the palmitoylation of a cysteine residue. MISCELLANEOUS: The rank order of affinity of this receptor to tachykinins is: neuromedin K > substance K > substance P. SIMILARITY: Belongs to the G-protein coupled receptor 1 family.

Specificity has been shown by western blot using rat brain homogenate. A band of 66 kDa, the theoretical MW of NK-3R, could be easily detected.
Application Information:
WB. A dilution of 1:500 to 1:2000 is recommended. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.

Type: Primary
Antigen: Neurokinin-3 Receptor
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: absolute C-terminal of rat NK-3 receptor protein (aa: 434-452)
Host: Rabbit
Isotype: IgG
Reactivity: Rat
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