Anti-ATG16 L1 Rabbit Polyclonal Antibody

Proveedor: Biosensis
BSENR-158-100EA 334 EUR
Anti-ATG16 L1 Rabbit Polyclonal Antibody
ATG16 L1 plays an essential role in autophagy. It is a homooligomer ant interacts with ATG5. Part of either the minor and major complexes respectively composed of 4 sets of ATG12-ATG5 and ATG16L1 (400 kDa) or 8 sets of ATG12-ATG5 and ATG16L1 (800 kDa). APG16 L1 localises to the cytoplasm, in particularly to preautophagosomal structure (PAS) where it is involved in the membrane targeting of ATG5. There are 5 named isoforms produced by alternative splicing. Genetic variation within ATG16 L1 are associated with susceptibility to inflammatory bowel disease type 1.

IHC, WB and ELISA confirmed the specificity for ATG16 L1.
Application Information:
IHC, immunofluorescence, WB. A dilution of 1:100 to 1:3000 dilution is recommended for these applications. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.

Type: Primary
Antigen: ATG16 L1
Clonality: Polyclonal
Conjugation: Unconjugated
Epitope: N-terminal of Human ATG16-L1
Host: Rabbit
Isotype: IgG
Reactivity: Human, Rat
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