Sephadex ion exchangers are produced by introducing functional groups onto the cross-linked dextran matrix.
- Strong anion exchanger suitable batch techniques
- High binding capacities
- Stable to all commonly used aqueous buffers additives such as 8 M urea and 6 M guanidine hydrochloride
- Avoid using oxidising agents and dextranase
Different types of ion exchangers (DEAE, QAE and CM) and two different porosities (A-25/C-25 and A-50/C-50) are available.
These groups are attached to glucose units in the matrix by stable ether linkages.